Addy Osmani has written a really nice article to discuss an effective set of Patterns For Large-Scale JavaScript Application Architecture. Large-scale JavaScript apps are non-trivial applications requiring significant developer effort to maintain, where most heavy lifting of data manipulation and display falls to the browser.

If working on a significantly large JavaScript application, remember to dedicate sufficient time to planning the underlying architecture that makes the most sense. It’s often more complex than you may initially imagine. Take a look at this great article, I am sure you will learnt a lot too.

Source: Patterns For Large-Scale JavaScript Application Architecture